Emotional Wellbeing

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6 Proven Ways How CBD Oil Helps With Depression

Depression may seem a mere state of irritating moodiness, but it is listed among the most severe diseases acknowledged by WHO. Unfortunately, there is no immunity against depression. It can attack anyone, especially after a series of stressful life events. For the treatment of depression, experts recommend the combination of traditional and non-traditional therapies, such as medications, lifestyle changes, and treatment.

CBD emerges as a solution for depression


Recently, CBD (cannabidiol) has received positive reviews as a potential treatment against depression. It is considered to hold a notable antidepressant effect, owing to its positive relations with the brain’s serotonin receptors, which have already been successfully treated on animals. Moreover, unlike other compounds found in cannabis, such as THC (tetrahydrocannabinol), CBD doesn’t make people “high.” Consumers across the globe have praised CBD as a potent anti-stress remedy. Nowadays, numerous CBD products are available on the market. One such CBD product line is Nuleaf Naturals CBD, which has the highest cannabinoid content possible to provide you with good results.

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CBD oil




Right from relieving chronic pain to anxiety, numerous beneficial properties of CBD oil help enhance our physical and mental health. But, the treatment of depression is the third most common use of CBD oil. Let’s explore six proven positive effects of CBD oil for the treatment of depression.

1.    Can Increase the Birth of New Brain Cells

A protein called brain-derived neurotrophic factor (BDNF) promotes birth, development, and regeneration of our brain cells. Depressed people often have low levels of BDNF.

CBD has shown to increase BDNF and strengthen the connections between the brain regions that affect emotions, fear memory, and thinking. There is a probability that depression shrinks the hippocampus with time. CBD is known to promote the birth of new brain cells or neurogenesis in the hippocampus, which adds to the mood-enhancing effect.

2.    May Enhance Serotonin Activity

CBD oil can increase serotonin activity in the brain. Serotonin is popularly known as the “happiness neurotransmitter.” CBD has the ability to activate the 5HT1A receptors for serotonin. This eventually improves mood. Low serotonin activity in the brain causes depression, according to the “serotonin hypothesis.” Most of the antidepressant drugs, such as SSRIs increase serotonin by preventing its removal from synapses.

According to a study, CBD can induce antidepressant-like effects in mice. It increased the levels of serotonin and glutamate in the brain. The facilitation of 5-HT1A receptor-mediated neurotransmission mediates CBD-induced effects. This activates 5-HT1A, in turn, improving the overall mood in depressed people.

3.    Can Boost Natural Endocannabinoids

The endocannabinoid system in our body is made up of two receptors: CB1 and CB2. The naturally produced cannabinoids in our body, such as the anandamide, bind to and activate these receptors. CBD can increase anandamide, which is also known as the bliss molecule.

In various studies, anandamide reduced the symptoms of depression by activating both the serotonin and endocannabinoid pathways. Cannabinoid CB(1) receptor agonists and endocannabinoid enhancers such as fatty acid amide hydrolase (FAAH) possess antidepressant-like properties. They can enhance the central noradrenergic and serotonergic transmission, eventually promoting neurogenesis in the hippocampus.

4.    Can Increase Dopamine Levels

Dopamine is a chemical messenger in the nervous system that sends messages to nerve cells. It broadly affects how a person plans, thinks, or feels pleasure. Dopamine plays a vital role in mood, appreciation, and motivation. A person with proper levels of dopamine can easily reach goals of happiness and satisfaction. However, depressed people have low levels of dopamine.

CBD can increase dopamine levels in the brain that prevents possible burnout. CBD interacts with the dopamine receptors that help regulate cognition, motivation, and reward-seeking behavior.

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5.    May Enhance GABA Activity

Gamma-Aminobutyric acid or GABA is a main inhibitory neurotransmitter of the central nervous system. It blocks or inhibits certain brain signals that reduce neuronal (nerve cells) activity. This plays a significant role in cognitive functions and produces anti-anxiety or antidepressant effects.

CBD is found to have a “positive allosteric modulator” of the GABA-A receptor in the brain. CBD binds to the receptor and enhances the natural calming effect of GABA, thus reduces anxiety. Moreover, CBD mimics the sedating effects of Valium and other benzodiazepines, but it is safer than these drugs.

6.    Alternative to anti-depression drugs

Cannabis has been proven to be extremely safe and poses minimal risk to its consumers. As discussed above, many studies have shown that CBD possesses antidepressant effects and works in similar ways to some prescription drugs. Research has also quoted CBD as a new fast-acting antidepressant drug.

The antidepressant drugs prescribed have a long list of adverse side effects that make them a less beneficial option for the body. On the other hand, CBD is an extremely safe substance that does not account for any overdose-related deaths when used on its own.

 If you are looking for CBD products to aid you in your depression, check penguin cbd.

CBD oil

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Currently, CBD oil is listed among the most popular products for the treatment of depression but should be used after consultation with a physician. CBD oil can certainly alleviate depression, but when it comes to efficacy, the method of intake and daily dosage are essential. When using CBD, it is also crucial to pay attention to your body signals. It neither causes dependency nor addiction, but improves mood and increases the general sense of well-being. If you are willing to use CBD to alleviate the depressive symptoms in conjunction with your existing treatment, make sure to consult your doctor about the dosage and possible medication interactions.

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